Bio-protective effects of subsp. against aflatoxin b1 genotoxicity on human blood lymphocytes: a native probiotic strain isolated from Iranian camel milk.

Journal: Current medical mycology
Published Date: Dec 1, 2020

Abstract

BACKGROUND AND PURPOSE: Aflatoxin B1 is one of the main poisonous substances in certain kinds of fungi all over the world. The toxin is a serious health threat to humans and livestock, particularly via DNA damage, and induces multiple cancers. Probiotic agents have confirmed positive beneficial effects in DNA protection against various toxic compounds. In this regard, the present study aimed to investigate the bio-protective effects of a native subsp. NIMBB003 strain isolated from Iranian one-humped camel milk against AflatoxinB1 (AFB1)-induced genotoxicity damage, based on the micronucleus test as a genotoxicity monitoring method.

Authors

  • Parvaneh Afshar
    Department of Food Science and Technology, Islamic Azad University, Ayatollah Amoli Branch, Amol, Iran.
  • Leila Roozbeh Nasiraie
    Department of Food Science and Technology, Islamic Azad University, Nour Branch, Nour, Iran.
  • Mohammad Shokrzadeh
    Department of Toxicology and Pharmacology, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
  • Azade Ghorbani HasanSaraei
    Department of Food Science and Technology, Islamic Azad University, Ayatollah Amoli Branch, Amol, Iran.
  • Shahram Naghizadeh Raeisi
    Department of Food Science and Technology, Islamic Azad University, Ayatollah Amoli Branch, Amol, Iran.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals