Dictionary learning based image-domain material decomposition for spectral CT.

Journal: Physics in medicine and biology
Published Date:

Abstract

The potential huge advantage of spectral computed tomography (CT) is that it can provide accurate material identification and quantitative tissue information by material decomposition. However, material decomposition is a typical inverse problem, where the noise can be magnified. To address this issue, we develop a dictionary learning based image-domain material decomposition (DLIMD) method for spectral CT to achieve accurate material components with better image quality. Specifically, a set of image patches are extracted from the mode-1 unfolding of normalized material images decomposed by direct inversion to train a unified dictionary using the K-SVD technique. Then, the DLIMD model is established to explore the redundant similarities of the material images, where the split-Bregman is employed to optimize the model. Finally, more constraints (i.e. volume conservation and the bounds of each pixel within material maps) are integrated into the DLIMD model. Numerical phantom, physical phantom and preclinical experiments are performed to evaluate the performance of the proposed DLIMD in material decomposition accuracy, material image edge preservation and feature recovery.

Authors

  • Weiwen Wu
    Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing, 400044, China.
  • Haijun Yu
    Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing 400044, People's Republic of China.
  • Peijun Chen
    The Key Lab of Optoelectronic Technology and Systems of the Education Ministry of China, Chongqing University, Chongqing, China.
  • Fulin Luo
    State Key Laboratory of Information Engineering in Surveying, Mapping and Remote Sensing, Wuhan University, Wuhan 430079, People's Republic of China.
  • Fenglin Liu
    Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
  • Qian Wang
    Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China.
  • Yining Zhu
    Wuhan National Laboratory for Optoelectronics(WNLO), Huazhong University of Science and Technology(HUST), Wuhan, 430074, Hubei, People's Republic of China.
  • Yanbo Zhang
    Department of Psychiatry, University of Alberta, Edmonton, Canada.
  • Jian Feng
    Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing 400044, People's Republic of China.
  • Hengyong Yu
    Department of Electrical and Computer Engineering, University of Masachusetts Lowell, Lowell, MA 01854, USA.