Increased Thyroid-Hormone Requirements Consistent With Type 3 Deiodinase Induction Related to Ibrutinib in a Thyroidectomized Woman.

Journal: AACE clinical case reports
Published Date: Dec 28, 2020

Abstract

OBJECTIVE: Tyrosine-kinase inhibitors (TKIs) are chemotherapeutic agents associated with increased thyroid-hormone requirements and altered deiodinase activity. We present the first case to link these findings to the TKI ibrutinib.

Authors

  • Alon Yehuda Mazori
    Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Maria Skamagas
    Division of Endocrinology, Diabetes and Bone Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

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