Iatrogenic Cushing's syndrome as a consequence of nasal use of Betamethasone spray during pregnancy.

Journal: Acta endocrinologica (Bucharest, Romania : 2005)
Published Date: Jan 1, 2020

Abstract

INTRODUCTION: Glucocorticoids (GC) are largely used for their anti-inflammatory and immunosuppressive effects. Until recently "local" administration (inhalation, topical, intra-articular, ocular and nasal) was considered devoid of important systemic side effects, but there is no administration form, dosing or treatment duration for which the risk of iatrogenic Cushing's syndrome (CS) and consequent adrenal insufficiency (AI) can be excluded with certainty.

Authors

  • A Scutelnicu
    "Filantropia" Clinical Hospital of Obstetrics and Gynecology, Bucharest, Romania.
  • A M Panaitescu
    "Filantropia" Clinical Hospital of Obstetrics and Gynecology, Bucharest, Romania.
  • A M Ciobanu
    "Filantropia" Clinical Hospital of Obstetrics and Gynecology, Bucharest, Romania.
  • N Gica
    "Filantropia" Clinical Hospital of Obstetrics and Gynecology, Bucharest, Romania.
  • R Botezatu
    "Filantropia" Clinical Hospital of Obstetrics and Gynecology, Bucharest, Romania.
  • G Peltecu
    "Filantropia" Clinical Hospital of Obstetrics and Gynecology, Bucharest, Romania.
  • M L Gheorghiu
    "C.I.Parhon" National Institute of Endocrinology - Neuroendocrinology, Bucharest, Romania.

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