Intravenous Lignocaine-Fentanyl Versus Epidural Ropivacaine-Fentanyl for Postoperative Analgesia After Major Abdominal Oncosurgery: A Pilot Prospective Randomised Study.

Journal: Turkish journal of anaesthesiology and reanimation
Published Date: Feb 17, 2020

Abstract

OBJECTIVE: Epidural injection of local anaesthetics and intravenous opioid injection are two common analgesic strategies following major abdominal oncosurgery. However, epidural local anaesthetics may cause haemodynamic instability while opioid injection is associated with sedation and postoperative ileus. Intravenous lignocaine is also used for postoperative analgesia, and combined use of opioids plus lignocaine can reduce the doses and adverse effects of the individual drugs. This study therefore compared the analgesic efficacy of intravenous lignocaine-fentanyl (IV) to epidural ropivacaine-fentanyl (EPI) after major abdominal oncosurgery.

Authors

  • Rudranil Nandi
    Department of Onco-anaesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
  • Seema Mishra
    Department of Onco-anaesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
  • Rakesh Garg
    Department of Onco-anaesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
  • Vinod Kumar
    Department of Onco-anaesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
  • Nishkarsh Gupta
    Department of Onco-anaesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
  • Sachidanand Jee Bharati
    Department of Onco-anaesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
  • Sushma Bhatnagar
    Department of Onco-anaesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.

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