Diagnostic Value of Pyruvate Kinase Isoenzyme Type M2 in Colon Cancer Proven with Colonoscopy.

Journal: Advanced biomedical research
Published Date: Dec 23, 2020

Abstract

BACKGROUND: Colonoscopy is the gold standard for colon cancer screening; it is also associated with a high cost and complication. Proliferating cells, in particular tumor cells, express a dimeric isoenzyme of pyruvate kinase, termed M2 pyruvate kinase (M2-PK). The aim of this study was to determine the diagnostic accuracy of fecal M2-PK for colon cancer.

Authors

  • Hamid Kalantari
    Department of Internal Medicine, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Mahsa Khodadoostan
    Department of Internal Medicine, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Majid Yaran
    Department of Laboratory Medicine, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Abdolrasoul Tavakoli
    Department of Internal Medicine, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.

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