Leishmanicidal, Trypanocidal and Antioxidant Activity of Amyrin-Rich Extracts from Cambess.

Journal: Iranian journal of pharmaceutical research : IJPR
Published Date: Jan 1, 2020

Abstract

AIMS: This study aimed to characterize and evaluate leishmanicidal and trypanocidal action as well as cytotoxicity on macrophages and antioxidant ability of extracts, obtained by supercritical CO and ultrasound-assisted extractions of Uvaia () leaves.

Authors

  • João H de Souza
    Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel/PR, Brazil.
  • Alexandra Michelon
    Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel/PR, Brazil.
  • Fernanda W Banhuk
    Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel/PR, Brazil.
  • Izabela V Staffen
    Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel/PR, Brazil.
  • Elissandro J Klein
    Laboratory of Engineering and Environmental Processes, Department of Process and Product Development, State University of Campinas, Campinas/SP, Brazil.
  • Edson A da Silva
    Laboratory of Biotechnological Processes and Separation, Center of Exact and Technological Sciences, Western Parana State University, Toledo/PR, Brazil.
  • Rafael A Menolli
    Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel/PR, Brazil.

Keywords

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