Harmine protects mercuric chloride kidney-induced injury by antioxidant activity in male mice: a biochemical and histological study.

Journal: Research in pharmaceutical sciences
Published Date: Nov 27, 2020

Abstract

BACKGROUND AND PURPOSE: Mercuric chloride (Merc) can cause kidney toxicity. Harmine (Harm), an herbal alkaloid has various pharmacological and medicinal effects mainly because of its antioxidant activity. In this study, therefore, Harm's protective mechanisms on Merc-induced nephrotoxicity in BALB/c male mice were investigated.

Authors

  • Cyrus Jalili
    Department of Anatomical Sciences, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, I.R. Iran.
  • Nasim Akhshi
    Department of Anatomical Sciences, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, I.R. Iran.
  • Iraj Rashidi
    Department of Anatomical Sciences, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, I.R. Iran.
  • Ali Ghanbari
    Department of Anatomical Sciences, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, I.R. Iran.

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