Standardized Fraction Arrested SiHa Cells at G1/S and Induced Apoptosis via Upregulation of p53.

Journal: Journal of pharmacy & bioallied sciences
Published Date: Nov 5, 2020

Abstract

INTRODUCTION: Cervical cancer is a leading cause of death in women. Current cancer treatment comes with side effects. has been known traditionally to treat cancer. This study was aimed to characterize standardized fraction (SF1) and to investigate its anticancer mechanism against SiHa cells.

Authors

  • Nik Aina Syazana Nik Zainuddin
    Biomedicine Programme, School of Health Sciences, Universiti Sains Malaysia (USM) Health Campus, 16150 Kota Bharu, Kelantan, Malaysia.
  • Hussin Muhammad
    Toxicology and Pharmacology Unit, Herbal Medicine Research Centre, Institute for Medical Research (IMR), 50588 Kuala Lumpur, Malaysia.
  • Nik Fakhuruddin Nik Hassan
    Forensic Science Programme, School of Health Sciences, Universiti Sains Malaysia (USM) Health Campus, 16150 Kota Bharu, Kelantan, Malaysia.
  • Nor Hayati Othman
    Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia (USM) Health Campus, 16150 Kota Bharu, Kelantan, Malaysia.
  • Yusmazura Zakaria
    Biomedicine Programme, School of Health Sciences, Universiti Sains Malaysia (USM) Health Campus, 16150 Kota Bharu, Kelantan, Malaysia.

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