Prognostic Value and Reproducibility of AI-assisted Analysis of Lung Involvement in COVID-19 on Low-Dose Submillisievert Chest CT: Sample Size Implications for Clinical Trials.

Journal: Radiology. Cardiothoracic imaging
Published Date: Oct 22, 2020

Abstract

PURPOSE: To compare the prognostic value and reproducibility of visual versus AI-assisted analysis of lung involvement on submillisievert low-dose chest CT in COVID-19 patients.

Authors

  • Christopher Gieraerts
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Anthony Dangis
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Lode Janssen
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Annick Demeyere
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Yves De Bruecker
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Nele De Brucker
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Annelies van Den Bergh
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Tine Lauwerier
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • André Heremans
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Eric Frans
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Michaël Laurent
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Bavo Ector
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • John Roosen
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Annick Smismans
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Johan Frans
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Marc Gillis
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).
  • Rolf Symons
    Department of Radiology - Imelda Hospital, Bonheiden, Belgium (C.G., A.D., L.J., A.D., Y.D.B., R.S.); Department of Pulmonology - Imelda Hospital, Bonheiden, Belgium (N.D.B., A.V.D.B., T.L., A.H., E.F.); Department of Intensive Care Medicine - Imelda Hospital, Bonheiden, Belgium (E.F.); Department of Geriatrics - Imelda Hospital, Bonheiden, Belgium (M.L.); Department of Cardiology - Imelda Hospital, Bonheiden, Belgium (B.E., J.R.); Department of Medical Microbiology - Imelda Hospital, Bonheiden, Belgium (A.S., J.F.); Department of Emergency Medicine - Imelda Hospital, Bonheiden, Belgium (M.G.).

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