Next Generation Techniques for Determination of Protein-Protein Interactions: Beyond the Crystal Structure.

Journal: Current pathobiology reports
Published Date: Jul 1, 2019

Abstract

PURPOSE OF REVIEW: We discuss recent advancements in structural biology methods for investigating sites of protein-protein interactions. We will inform readers outside the field of structural biology about techniques beyond crystallography, and how these different technologies can be utilized for drug development.

Authors

  • Rachel Carter
    Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA.
  • Alessandra Luchini
    Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA.
  • Lance Liotta
    Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA.
  • Amanda Haymond
    Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA.

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