A review on retinopathy of prematurity.

Journal: Medical hypothesis, discovery & innovation ophthalmology journal
Published Date: Feb 1, 2025

Abstract

BACKGROUND: Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. It predominantly affects preterm infants with very low birth weights or extreme prematurity. Aberrant retinal vascular development, driven by hyperoxia and hypoxia-induced neovascularization, is central to ROP pathogenesis. This review explores the relationship between maternal health and ROP, evaluates current prevention strategies, assesses innovations in diagnostic and screening technologies, reviews contemporary treatments, and identifies future research directions.

Authors

  • Pegah Rashidian
    Vali-e-Asr Reproductive Health Research Center, Family Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
  • Shaghayegh Karami
    Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.
  • Seyyed Amirhossein Salehi
    Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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