Fibroblast growth factor 23 and tubular sodium handling in young patients with incipient chronic kidney disease.
Journal:
Clinical kidney journal
Published Date:
Jul 3, 2019
Abstract
BACKGROUND: Experimental studies have shown fibroblast growth factor 23 FGF23)-mediated upregulation of the distal tubule sodium/chloride (NaCl) co-transporter leading to increased Na reabsorption, volume expansion and hypertension. However, data on the associations of FGF23 with renal Na regulation and blood pressure (BP) are lacking in young CKD patients.
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