Identifying shared diagnostic genes and mechanisms in vascular dementia and Alzheimer's disease via bioinformatics and machine learning.

Journal: Journal of Alzheimer's disease reports
Published Date: Nov 24, 2024

Abstract

BACKGROUND: Alzheimer's disease (AD) and vascular dementia (VaD) share overlapping pathophysiological characteristics, yet comparative genetic studies are rare. Understanding these overlaps may aid in identifying common diagnostic markers and therapeutic targets.

Authors

  • Wanning Zheng
    Brain center, Zhejiang Hospital, Hangzhou, China.
  • Dongdong Lin
    Brain center, Zhejiang Hospital, Hangzhou, China.
  • Shunan Shi
    Brain center, Zhejiang Hospital, Hangzhou, China.
  • Jiayi Ren
    Department of Respiratory Medicine, Sir Run Run Shaw Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
  • Jiong Wu
    Brain center, Zhejiang Hospital, Hangzhou, China.
  • Ming Wang
    Brain center, Zhejiang Hospital, Hangzhou, China.
  • Shu Wan
    Brain center, Zhejiang Hospital, Hangzhou, China.

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