An Study on the Cytotoxicity and Genotoxicity of Silver Sulfide Quantum Dots Coated with Meso-2,3-dimercaptosuccinic Acid.

Journal: Turkish journal of pharmaceutical sciences
Published Date: Jul 10, 2019

Abstract

OBJECTIVES: Silver sulfide (AgS) quantum dots (QDs) are highly promising nanomaterials in bioimaging systems due to their high activities for both imaging and drug/gene delivery. There is insufficient research on the toxicity of AgS QDs coated with meso-2,3-dimercaptosuccinic acid (DMSA). In this study, we aimed to determine the cytotoxicity of AgS QDs coated with DMSA in Chinese hamster lung fibroblast (V79) cells over a wide range of concentrations (5-2000 μg/mL).

Authors

  • Deniz Özkan Vardar
    Hitit University, Sungurlu Vocational High School, Health Programs, Çorum, Turkey.
  • Sevtap Aydin
    Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey.
  • İbrahim Hocaoğlu
    Koç University, Graduate School of Materials Science and Engineering, İstanbul, Turkey.
  • Havva Yağci Acar
    Koç University, College of Sciences, Department of Chemistry, İstanbul, Turkey.
  • Nursen Başaran
    Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey.

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