Redirection of transfusion waste and by-products for xeno-free research applications.

Journal: Journal of clinical and translational research
Published Date: Nov 9, 2019

Abstract

BACKGROUND AND AIM: Whole blood is processed to derive a red cell concentrate, plasma, and buffy coat (BC) (from which platelets can be further extracted). Unused plasma and BCs are common in most blood establishments and considered a liability. The redirection of these products to xeno-free applications is not complicated or time-consuming and cannot only benefit the research recipients but also the blood establishment suppliers interested in research collaboration. The aim of this study is to describe a diverse yet by no means an exhaustive list of options for preparing blood products for research applications.

Authors

  • Vanessa Zammit
    National Blood Transfusion Service, St. Luke's Hospital, G'Mangia, PTA1010, Malta.
  • Mark Farrugia
    Centre for Molecular Medicine and Biobanking, Faculty of Medicine and Surgery, University of Malta, Msida, MSD2080, Malta.
  • Byron Baron
    Centre for Molecular Medicine and Biobanking, Faculty of Medicine and Surgery, University of Malta, Msida, MSD2080, Malta.

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