Leveraging machine learning and rule extraction for enhanced transparency in emergency department length of stay prediction.

Journal: Frontiers in digital health
Published Date:

Abstract

This study aims to address the critical issue of emergency department (ED) overcrowding, which negatively affects patient outcomes, wait times, and resource efficiency. Accurate prediction of ED length of stay (LOS) can streamline operations and improve care delivery. We utilized the MIMIC IV-ED dataset, comprising over 400,000 patient records, to classify ED LOS into short (≤4.5 hours) and long (>4.5 hours) categories. Using machine learning models, including Gradient Boosting (GB), Random Forest (RF), Logistic Regression (LR), and Multilayer Perceptron (MLP), we identified GB as the best performing model outperforming the other models with an AUC of 0.730, accuracy of 69.93%, sensitivity of 88.20%, and specificity of 40.95% on the original dataset. In the balanced dataset, GB had an AUC of 0.729, accuracy of 68.86%, sensitivity of 75.39%, and specificity of 58.59%. To enhance interpretability, a novel rule extraction method for GB model was implemented using relevant important predictors, such as triage acuity, comorbidity scores, and arrival methods. By combining predictive analytics with interpretable rule-based methods, this research provides actionable insights for optimizing patient flow and resource allocation. The findings highlight the importance of transparency in machine learning applications for healthcare, paving the way for future improvements in model performance and clinical adoption.

Authors

  • Waqar A Sulaiman
    Department of Computer Science and Biomedical Engineering Research Centre, University of Cyprus, Nicosia, Cyprus.
  • Charithea Stylianides
    CYENS Centre of Excellence, Nicosia, Cyprus.
  • Andria Nikolaou
    Department of Computer Science and Biomedical Engineering Research Centre, University of Cyprus, Nicosia, Cyprus.
  • Zinonas Antoniou
    Research & Development Department, 3AHealth, Nicosia, Cyprus.
  • Ioannis Constantinou
    Research & Development Department, 3AHealth, Nicosia, Cyprus.
  • Lakis Palazis
    Department of Intensive Care Medicine, Limassol General Hospital, State Health Services Organisation, Nicosia, Cyprus.
  • Anna Vavlitou
    Department of Intensive Care Medicine, Limassol General Hospital, State Health Services Organisation, Nicosia, Cyprus.
  • Theodoros Kyprianou
    Department of Critical Care and Emergency Medicine, Medical School, University of Nicosia, Nicosia, Cyprus.
  • Efthyvoulos Kyriacou
    Department of Electrical Engineering, Computer Engineering and Informatics, Cyprus University of Technology, Limassol, Cyprus.
  • Antonis Kakas
    Department of Computer Science and Biomedical Engineering Research Centre, University of Cyprus, Nicosia, Cyprus.
  • Marios S Pattichis
    Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, NM, United States.
  • Andreas S Panayides
    CYENS Centre of Excellence, Nicosia, Cyprus.
  • Constantinos S Pattichis
    Department of Computer Science and Biomedical Engineering Research Centre, University of Cyprus, Nicosia, Cyprus.

Keywords

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