Spatial Radiation Dose Influence on Xerostomia Recovery and Its Comparison to Acute Incidence in Patients With Head and Neck Cancer.

Journal: Advances in radiation oncology
Published Date: Aug 31, 2019

Abstract

PURPOSE: Radiation-induced xerostomia is one of the most prevalent symptoms during and after head and neck cancer radiation therapy (RT). We aimed to discover the spatial radiation dose-based (voxel dose) importance pattern in the major salivary glands in relation to the recovery of xerostomia 18 months after RT, and to compare the recovery voxel dose importance pattern to the acute incidence (injury) pattern.

Authors

  • Yue Guo
    Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland.
  • Wei Jiang
    Department of Civil Engineering, Johns Hopkins System Institute, Johns Hopkins University, Baltimore, Maryland.
  • Pranav Lakshminarayanan
    Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland.
  • Peijin Han
    Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland.
  • Zhi Cheng
    Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland.
  • Michael Bowers
    Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland.
  • Xuan Hui
    Department of Public Health Sciences, University of Chicago, Chicago, Illinois; and.
  • Ilya Shpitser
    Department of Computer Science, Johns Hopkins University, Baltimore, Maryland.
  • Sauleh Siddiqui
    Department of Civil Engineering, Johns Hopkins System Institute, Johns Hopkins University, Baltimore, Maryland.
  • Russell H Taylor
    Johns Hopkins University, Baltimore, MD, USA.
  • Harry Quon
    Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland.
  • Todd McNutt
    Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals