Adipocyte Fatty Acid-Binding Protein 4 is Altered in Growth Discordant Dichorionic, but not in Monochorionic Twins.

Journal: Journal of the Endocrine Society
Published Date: Dec 21, 2019

Abstract

CONTEXT: The fetal period has a critical and long-lasting impact on the regulation of metabolic processes and a life-long predisposition for obesity and metabolic syndrome. The exact mechanisms are unknown, but epigenetic regulation likely plays a major role. Twins represent an excellent model to study these mechanisms, as they share the same intrauterine environment and similar or even the same genetic information. We examined cord blood levels of adipocyte fatty-acid binding protein 4 (A-FABP or FABP4), a novel adipokine correlated with obesity and metabolic disease in children and adults.

Authors

  • Susanne Schrey-Petersen
    Department of Obstetrics, University of Leipzig, Leipzig, Germany.
  • Saskia Bäumer
    Department of Obstetrics, University of Leipzig, Leipzig, Germany.
  • Ulrike Lössner
    Department of Internal Medicine III, University of Leipzig, Leipzig, Germany.
  • Holger Stepan
    Department of Obstetrics, University of Leipzig, Leipzig, Germany.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals