Comparison of a Novel Homogeneous Cyclic Amp Assay and a Luciferase Assay for Measuring Stimulating Thyrotropin-Receptor Autoantibodies.

Journal: European thyroid journal
Published Date: Nov 27, 2019

Abstract

OBJECTIVE: Stimulating thyrotropin-receptor antibodies (TSAb) cause Graves' disease (GD). We tested a novel homogeneous fluorescent 3',5' cyclic adenine monophosphate (cAMP) assay for the detection of TSAb in a bioassay.

Authors

  • Tanja Diana
    Molecular Thyroid Research Laboratory, Department of Medicine I, Johannes Gutenberg University (JGU) Medical Center, Mainz, Germany.
  • Paul D Olivo
    Department of Molecular Microbiology, Washington University Medical School, St. Louis, Missouri, USA.
  • Yie-Hwa Chang
    Mediomics, LLC, St. Louis, Missouri, USA.
  • Christian Wüster
    Endocrine Laboratory and Practice Prof. Wüster, Mainz, Germany.
  • Michael Kanitz
    Molecular Thyroid Research Laboratory, Department of Medicine I, Johannes Gutenberg University (JGU) Medical Center, Mainz, Germany.
  • George J Kahaly
    Molecular Thyroid Research Laboratory, Department of Medicine I, Johannes Gutenberg-University (JGU) Medical Center, Mainz, Germany.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals