Anti- Activity of Extracts from Argentinean Asteraceae Species.

Journal: Iranian journal of pharmaceutical research : IJPR
Published Date: Jan 1, 2019

Abstract

The anti- activity of extracts from 13 Argentinean Asteraceae species was determined. Dichloromethane and methanol extracts of , , and were evaluated against epimastigotes, , , , , and dichloromethane extracts showed trypanocidal activity with inhibitions higher than 60% at a concentration of 10 µg/mL. The methanol extracts of and were the most active with inhibitions of 70.1 and 77.7%, respectively at 10 µg/mL. The chromatographic profiles of the most active extracts showed bands and major peaks that could be attributed to flavonoids and terpenoid compounds.

Authors

  • Mariana G Selener
    Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
  • Orlando Elso
    Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
  • Carla Grosso
    Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
  • Jimena Borgo
    Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
  • María Clavin
    Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
  • Emilio L Malchiodi
    Cátedra de Inmunología, Instituto de Estudios de la Inmunidad Humoral (IDEHU) (UBA-CONICET), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
  • Silvia I Cazorla
    Centro de Referencia para Lactobacilos (CERELA) (CONICET), San Miguel de Tucumán, Argentina.
  • Flavia Flavia
    Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
  • Valeria P Sülsen
    Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.

Keywords

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