Deep learning based classification of unsegmented phonocardiogram spectrograms leveraging transfer learning.

Journal: Physiological measurement
Published Date:

Abstract

Cardiovascular diseases (CVDs) are a main cause of deaths all over the world. This research focuses on computer-aided analysis of phonocardiogram (PCG) signals based on deep learning that can enable improved and timely detection of heart abnormalities. The two widely used publicly available PCG datasets are from the PhysioNet/CinC (2016) and PASCAL (2011) challenges. The datasets are significantly different in terms of the tools used for data acquisition, clinical protocols, digital storages and signal qualities, making it challenging to process and analyze.In this work, we have used short-time Fourier transform-based spectrograms to learn the representative patterns of the normal and abnormal PCG signals. Spectrograms generated from both the datasets are utilized to perform four different studies: (i) train, validate and test different variants of convolutional neural network (CNN) models with PhysioNet dataset, (ii) train, validate and test the best performing CNN structure on the PASCAL dataset, as well as (iii) on the combined PhysioNet-PASCAL dataset and (iv) finally, the transfer learning technique is employed to train the best performing pre-trained network from the first study with PASCAL dataset.The first study achieves an accuracy, sensitivity, specificity, precision and F1 scores of 95.75%, 96.3%, 94.1%, 97.52%, and 96.93%, respectively, while the second study shows accuracy, sensitivity, specificity, precision and F1 scores of 75.25%, 74.2%, 76.4%, 76.73%, and 75.42%, respectively. The third study shows accuracy, sensitivity, specificity, precision and F1 scores of 92.7%, 94.98%, 89.95%, 95.3% and 94.6%, respectively. Finally, the fourth study shows a precision of 96.98% on the noisy PASCAL dataset with transfer learning approach.The proposed approach employs a less complex and relatively light custom CNN model that outperforms most of the recent competing studies by achieving comparatively high classification accuracy and precision, making it suitable for screening CVDs using PCG signals.

Authors

  • Kaleem Nawaz Khan
    AI in Healthcare, Intelligent Information Processing Lab, National Center of Artificial Intelligence, UET Peshawar, Pakistan.
  • Faiq Ahmad Khan
    AI in Healthcare, Intelligent Information Processing Lab, National Center of Artificial Intelligence, UET Peshawar, Pakistan.
  • Anam Abid
    AI in Healthcare, Intelligent Information Processing Lab, National Center of Artificial Intelligence, UET Peshawar, Pakistan.
  • Tamer Olmez
    Department of Electronics and Communication Engineering, Istanbul Technical University, Istanbul, Turkey.
  • Zumray Dokur
    Department of Electronics and Communication Engineering, Istanbul Technical University, 34469, Istanbul, Turkey.
  • Amith Khandakar
    Department of Electrical Engineering, Qatar University, Doha 2713, Qatar.
  • Muhammad E H Chowdhury
    Department of Electrical Engineering, Qatar University, Doha 2713, Qatar.
  • Muhammad Salman Khan
    Department of Electrical Engineering (JC), University of Engineering and Technology, Peshawar, Pakistan. Electronic address: salmankhan@uetpeshawar.edu.pk.