Cyclin D1, Caspase 9 and P53 Expressions in T47D Cell Lines after Treatment of , (Lour.) Spreng. Leaves Ethanolic Extract Nanoparticles.

Journal: Open access Macedonian journal of medical sciences
Published Date:

Abstract

BACKGROUND: The application of nanotechnology is aimed to enhance the capability of the chemical compounds of (Lour.) Spreng. leaves activity. The contact area of the particle surface becomes larger in nano size, which can increase the amount of the isolated active substance. The nanoparticles of this extract exhibited the most effective impact in decreasing the cell number of T47D by induction of apoptosis and arresting the cell cycle.

Authors

  • Poppy Anjelisa Zaitun Hasibuan
    Department of Pharmacology, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.
  • Sumaiyah Sumaiyah
    Departement of Technology Pharmacy, Faculty of Pharmacy, Universitas Sumatera Utara, Medan 20155, Indonesia.

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