A Three-Gene Classifier Associated With MicroRNA-Mediated Regulation Predicts Prostate Cancer Recurrence After Radical Prostatectomy.

Journal: Frontiers in genetics
Published Date: Feb 4, 2020

Abstract

BACKGROUND AND OBJECTIVE: After radical prostatectomy (RP), prostate cancer (PCa) patients may experience biochemical recurrence (BCR) and clinical recurrence, which remains a dominant issue in PCa treatment. The purpose of this study was to identify a protein-coding gene classifier associated with microRNA (miRNA)-mediated regulation to provide a comprehensive prognostic index to predict PCa recurrence after RP.

Authors

  • Bo Cheng
    Department of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Qidan He
    Department of Gastrointestinal Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Yong Cheng
    Department of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Haifan Yang
    Department of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Lijun Pei
    Department of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Qingfu Deng
    Department of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Hao Long
    Department of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Likun Zhu
    Department of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
  • Rui Jiang
    Department of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

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