SAMbinder: A Web Server for Predicting S-Adenosyl-L-Methionine Binding Residues of a Protein From Its Amino Acid Sequence.

Journal: Frontiers in pharmacology
Published Date: Jan 30, 2020

Abstract

MOTIVATION: S-adenosyl-L-methionine (SAM) is an essential cofactor present in the biological system and plays a key role in many diseases. There is a need to develop a method for predicting SAM binding sites in a protein for designing drugs against SAM associated disease. To the best of our knowledge, there is no method that can predict the binding site of SAM in a given protein sequence.

Authors

  • Piyush Agrawal
    Department of Computational Biology, Indraprastha Institute of Information Technology, New Delhi, India.
  • Gaurav Mishra
    Department of Computational Biology, Indraprastha Institute of Information Technology, New Delhi, India.
  • Gajendra P S Raghava
    Department of Computational Biology, Indraprastha Institute of Information Technology, New Delhi, India.

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