Technical Considerations and Confounders for Urine CXCL10 Chemokine Measurement.

Journal: Transplantation direct
Published Date: Dec 24, 2019

Abstract

BACKGROUND: The urine C-X-C motif chemokine 10 (CXCL10) is a promising screening biomarker for renal allograft rejection. The aim of the study was to investigate important technical and biological aspects as well as potential confounders when measuring urine CXCL10.

Authors

  • Joelle Handschin
    Transplantation Immunology, Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Patricia Hirt-Minkowski
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
  • Gideon Hönger
    Transplantation Immunology, Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Sandra Mitrovic
    Clinical Chemistry, Department of Laboratory Medicine, University Hospital Basel, Basel, Switzerland.
  • Spasenija Savic Prince
    Institute for Pathology, University Hospital Basel, Basel, Switzerland.
  • Julie Ho
    Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada.
  • Peter Nickerson
    Transplantation and Nephrology, University of Manitoba, Winnipeg, Manitoba, Canada.
  • Stefan Schaub
    Transplantation Immunology, Department of Biomedicine, University of Basel, Basel, Switzerland.

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