The impact of architectural modifications on relative resistance to fluid flow in ventricular catheters.

Journal: Frontiers in bioengineering and biotechnology
Published Date: Jan 29, 2025

Abstract

INTRODUCTION: Although many ventricular catheter designs exist for hydrocephalus treatment, few standardized studies assess outflow resistance and the impact of design modifications on shunt drainage. This study represents the assessment of various architectural modifications on catheter flow rate and pressure, focusing on bulk outflow dynamics and occlusion with whole blood-inoculated cerebrospinal fluid.

Authors

  • Rajesh Kumar Madhavan
    Department of Biological Sciences, Wayne State University, Detroit, MI, United States.
  • Ahmad Faryami
    Department of Biomedical Engineering, Wayne State University, Detroit, MI, United States.
  • Nathan Tappen
    Department of Chemical Engineering, Wayne State University, Detroit, MI, United States.
  • Pranav Gopalakrishnan
    School of Medicine, Wayne State University, Detroit, MI, United States.
  • Shaheer H Ajaz
    Department of Biomedical Engineering, Wayne State University, Detroit, MI, United States.
  • Carolyn A Harris
    Department of Chemical Engineering, Wayne State University, Detroit, MI, United States.

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