Antiepileptic and anti-neuroinflammatory effects of red ginseng in an intrahippocampal kainic acid model of temporal lobe epilepsy demonstrated by electroencephalography.

Journal: Yeungnam University journal of medicine
Published Date: Dec 31, 2018

Abstract

BACKGROUND: Chronic inflammation can lower the seizure threshold and have influence on epileptogenesis. The components of red ginseng (RG) have anti-inflammatory effects. The abundance of peripherally derived immune cells in resected epileptic tissue suggests that the immune system is a potential target for anti-epileptogenic therapies. The present study used continuous electroencephalography (EEG) to evaluate the therapeutic efficacy of RG in intrahippocampal kainic acid (IHKA) animal model of temporal lobe epilepsy.

Authors

  • Ju Young Kim
    Department of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea.
  • Jin Hyeon Kim
    Department of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea.
  • Hee Jin Lee
    Department of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea.
  • Sang Hoon Kim
    Department of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea.
  • Young Jin Jung
    Department of Neurosurgery, Yeungnam University College of Medicine, Daegu, Korea.
  • Hee-Young Lee
    Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Korea.
  • Hee Jaung Kim
    Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Korea.
  • Sae Yoon Kim
    Department of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals