The first report on the antimicrobial activities of extracts of leaves of .
Journal:
Saudi journal of biological sciences
Published Date:
May 24, 2018
Abstract
The increasing resistance of infectious microbial organisms to the existing arsenal of antibiotic drugs is on the rise. There is a growing demand for the new antibiotics that are cost effective and easily available to the common people. In search of new antimicrobial entities, this report deals with the antimicrobial activities of the crude extracts of leaves of . The methanolic extract and its sub-fractions namely -hexane, chloroform, ethyl acetate, -butanol and residual water fraction were screened against a range of 30 different bacterial strains and their zones of inhibition (ZI) and minimum inhibitory concentration (MIC) were subsequently evaluated. Methanolic extract has shown activity against all the tested microorganisms such as and sp. with ZOI ranged from 10.3 to 29.0 mm Moreover, the MIC values of methanolic extract and its sub-fractions against the tested bacteria ranged from 0.8 to 5.1 mg/mL. GC-MS analysis of sub-fractions revealed the presence of mono (2-ethylexyl) 1,2-benzenedicarboxylate, diisooctyl-1,2-benzenedicarboxylate, 3,5-dehydro-6-methoxypivalate-cholest-22-ene-21-ol, and 3,5-bis (1,1-dimethylethyl)-4-hydroxybenzene-propanoic acid. This is the first report on the antimicrobial activities of leaves of
Authors
Keywords
No keywords available for this article.