Conversion from tacrolimus to belatacept improves renal function in kidney transplant patients with chronic vascular lesions in allograft biopsy.

Journal: Clinical kidney journal
Published Date: Dec 1, 2018

Abstract

BACKGROUND: Conversion from tacrolimus to belatacept has been shown to be beneficial for an increasing number of kidney transplant (KT) patients. Predicting factors for favorable outcomes are still unknown. We aimed to investigate whether histological vascular lesions at the time of conversion might correlate with greater improvement in renal function post-conversion.

Authors

  • María José Pérez-Sáez
    Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Bryant Yu
    Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Audrey Uffing
    Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Naoka Murakami
    Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Thiago J Borges
    Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Jamil Azzi
    Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Sandra El Haji
    Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Steve Gabardi
    Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Leonardo V Riella
    Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.

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