Chronic exposure to cadmium is associated with a marked reduction in glomerular filtration rate.

Journal: Clinical kidney journal
Published Date:

Abstract

BACKGROUND: Urinary 20-hydroxyeicosatetraenoic acid (20-HETE) has been associated with hypertension in women with elevated urinary cadmium (Cd) excretion rates. The present study investigates the urinary Cd and 20-HETE levels in relation to the estimated glomerular filtration rate (eGFR) and albumin excretion in men and women.

Authors

  • Soisungwan Satarug
    Centre for Kidney Disease Research, Faculty of Medicine, Translational Research Institute, University of Queensland, Brisbane, Australia.
  • Kanyarat Boonprasert
    Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand.
  • Glenda C Gobe
    Centre for Kidney Disease Research, Faculty of Medicine, Translational Research Institute, University of Queensland, Brisbane, Australia.
  • Ronnatrai Ruenweerayut
    Department of Internal Medicine, Mae Sot General Hospital, Tak Province, Thailand.
  • David W Johnson
    Centre for Kidney Disease Research, Faculty of Medicine, Translational Research Institute, University of Queensland, Brisbane, Australia.
  • Kesara Na-Bangchang
    Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand.
  • David A Vesey
    Centre for Kidney Disease Research, Faculty of Medicine, Translational Research Institute, University of Queensland, Brisbane, Australia.

Keywords

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