Obesity and chronic kidney disease progression-the role of a new adipocytokine: C1q/tumour necrosis factor-related protein-1.

Journal: Clinical kidney journal
Published Date: Oct 11, 2018

Abstract

BACKGROUND: Obesity is a risk factor for incident chronic kidney disease (CKD) in the general population. C1q/tumour necrosis factor-related protein 1 (CTRP1) is a new adipokine with multiple vascular and metabolic effects and may modulate the association between obesity and vascular diseases. The aim of the study is to explore potential links between obesity, CTRP1 levels and CKD progression.

Authors

  • Diego Barbieri
    Department of Nephrology, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
  • Marian Goicoechea
    Nephrology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
  • Maria Dolores Sánchez-Niño
    Spanish Kidney Research Network (REDinREN), Madrid, Spain.
  • Alberto Ortiz
    Department of Nephrology and Hypertension, IIS-Fundacion Jimenez Diaz, Universidad Autonoma de Madrid, Madrid, Spain.
  • Eduardo Verde
    Department of Nephrology, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
  • Ursula Verdalles
    Department of Nephrology, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
  • Ana Pérez de José
    Department of Nephrology, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
  • Andrés Delgado
    Department of Nephrology, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
  • Esther Hurtado
    Department of Nephrology, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
  • Luis Sánchez-Cámara
    Department of Nephrology, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
  • Nieves Lopez-Lazareno
    Biochemistry Department, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
  • Ana García-Prieto
    Department of Nephrology, Hospital General Universitario Gregorio Marañon, Madrid, Spain.
  • Jose Luño
    Department of Nephrology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

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