Physicochemical stability of oxycodone-ketamine solutions in polypropylene syringe and polyvinyl chloride bag for patient-controlled analgesia use.

Journal: European journal of hospital pharmacy : science and practice
Published Date: Oct 17, 2016

Abstract

OBJECTIVES: The study evaluated the stability of three combinations of oxycodone and ketamine diluted in normal saline (NS) after storage for 7 days at 23°C and exposed to light.

Authors

  • Mikaël Daouphars
    Department of Pharmacy, Cancer Centre Henri Becquerel, Rouen, France.
  • Charles-Henri Hervouët
    Department of Pharmacy, University Hospital Charles Nicolle, Rouen, France.
  • Pierre Bohn
    Nuclear Medicine Department, Cancer Centre Henri Becquerel, Rouen, France.
  • Delphine Martin
    Palliative Care Unit, University Hospital Charles Nicolle, Rouen, France.
  • Jean Rouvet
    Department of Pharmacy, Cancer Centre Henri Becquerel, Rouen, France.
  • Florence Basuyau
    Department of Pharmacy, Cancer Centre Henri Becquerel, Rouen, France.
  • Rémi Varin
    Department of Pharmacy, University Hospital Charles Nicolle, Rouen, France.

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