Quantitative Analysis of DCE and DSC-MRI: From Kinetic Modeling to Deep Learning.

Journal: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
Published Date:

Abstract

BACKGROUND: Perfusion MRI is a well-established imaging modality with a multitude of applications in oncological and cardiovascular imaging. Clinically used processing methods, while stable and robust, have remained largely unchanged in recent years. Despite promising results from novel methods, their relatively minimal improvement compared to established methods did not generally warrant significant changes to clinical perfusion processing.

Authors

  • Lukas T Rotkopf
    Department of Radiology, German Cancer Research Centre, Heidelberg, Germany.
  • Kevin Sun Zhang
    Department of Radiology, German Cancer Research Centre, Heidelberg, Germany.
  • Anoshirwan Andrej Tavakoli
    Division of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • David Bonekamp
    From the Department of Radiology (D.B., P.S., J.P.R., P.K., K.Y., M.F., H.P.S.), Division of Medical Image Computing (S.K., M.G., N.G., K.H.M.H.), Division of Statistics (M.W.), and Department of Medical Physics (T.A.K., F.D.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany (D.B., H.P.S., K.H.M.H.); and Departments of Urology (J.P.R., B.H., M.H., B.A.H.) and Neuroradiology (P.K.), University of Heidelberg Medical Center, Heidelberg, Germany.
  • Christian Herbert Ziener
    Department of Radiology, German Cancer Research Centre, Heidelberg, Germany.
  • Heinz-Peter Schlemmer
    From the Department of Radiology (D.B., P.S., J.P.R., P.K., K.Y., M.F., H.P.S.), Division of Medical Image Computing (S.K., M.G., N.G., K.H.M.H.), Division of Statistics (M.W.), and Department of Medical Physics (T.A.K., F.D.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany (D.B., H.P.S., K.H.M.H.); and Departments of Urology (J.P.R., B.H., M.H., B.A.H.) and Neuroradiology (P.K.), University of Heidelberg Medical Center, Heidelberg, Germany.