Kolaviron Protects the Prefrontal Cortex and Hippocampus against Histomorphological and Neurobehavioural Changes in Cuprizone Model of Multiple Sclerosis.

Journal: The Malaysian journal of medical sciences : MJMS
Published Date: Apr 27, 2018

Abstract

BACKGROUND: This study explored the efficacy of kolaviron-a biflavonoid complex isolated from the seeds of -in protecting against cuprizone (CPZ)-induced demyelination in both the prefrontal cortex and the hippocampus of Wistar rats.

Authors

  • Gabriel Olaiya Omotoso
    Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.
  • Olayemi Joseph Olajide
    Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.
  • Ismail Temitayo Gbadamosi
    Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.
  • Mikail Abiodun Rasheed
    Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.
  • Chiazokam Tochukwu Izuogu
    Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Nigeria.

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