Ablation of NTPDase2+ cells inhibits the formation of filiform papillae in tongue tip.

Journal: Animal models and experimental medicine
Published Date: Jul 28, 2018

Abstract

BACKGROUND: Lingual epithelia in the tongue tip are among the most rapidly regenerating tissues, but the mechanism of cell genesis in this tissue is still unknown. Previous study has suggested the existence of multiple stem cell pools in lingual epithelia and papillae. Like K14+ and Sox2+ cells, NTPDase2+ cells have characteristics of stem cells.

Authors

  • Feng Li
    Department of General Surgery, Shanghai Traditional Chinese Medicine (TCM)-INTEGRATED Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Bo-Wen Niu
    Department of Laboratory Animal Science Shanghai Public Health Clinical Center Fudan University Shanghai China.
  • Meng-Min Zhu
    Department of Laboratory Animal Science Shanghai Public Health Clinical Center Fudan University Shanghai China.

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