Large-scale medical image annotation with crowd-powered algorithms.

Journal: Journal of medical imaging (Bellingham, Wash.)
Published Date:

Abstract

Accurate segmentations in medical images are the foundations for various clinical applications. Advances in machine learning-based techniques show great potential for automatic image segmentation, but these techniques usually require a huge amount of accurately annotated reference segmentations for training. The guiding hypothesis of this paper was that crowd-algorithm collaboration could evolve as a key technique in large-scale medical data annotation. As an initial step toward this goal, we evaluated the performance of untrained individuals to detect and correct errors made by three-dimensional (3-D) medical segmentation algorithms. To this end, we developed a multistage segmentation pipeline incorporating a hybrid crowd-algorithm 3-D segmentation algorithm integrated into a medical imaging platform. In a pilot study of liver segmentation using a publicly available dataset of computed tomography scans, we show that the crowd is able to detect and refine inaccurate organ contours with a quality similar to that of experts (engineers with domain knowledge, medical students, and radiologists). Although the crowds need significantly more time for the annotation of a slice, the annotation rate is extremely high. This could render crowdsourcing a key tool for cost-effective large-scale medical image annotation.

Authors

  • Eric Heim
    German Cancer Research Center (DKFZ), Computer Assisted Medical Interventions, Heidelberg, Germany.
  • Tobias Roß
    German Cancer Research Center (DKFZ), Computer Assisted Medical Interventions, Heidelberg, Germany.
  • Alexander Seitel
    German Cancer Research Center (DKFZ), Computer Assisted Medical Interventions, Heidelberg, Germany.
  • Keno März
    German Cancer Research Center (DKFZ), Computer Assisted Medical Interventions, Heidelberg, Germany.
  • Bram Stieltjes
    University of Basel, University Hospital Basel, Radiology and Nuclear Medicine Clinic, Basel, Switzerland.
  • Matthias Eisenmann
    German Cancer Research Center (DKFZ), Computer Assisted Medical Interventions, Heidelberg, Germany.
  • Johannes Lebert
    University of Heidelberg, Department of General, Visceral and Transplant Surgery, Heidelberg, Germany.
  • Jasmin Metzger
    German Cancer Research Center (DKFZ), Medical Image Computing, Heidelberg, Germany.
  • Gregor Sommer
    University of Basel, University Hospital Basel, Radiology and Nuclear Medicine Clinic, Basel, Switzerland.
  • Alexander W Sauter
    University of Basel, University Hospital Basel, Radiology and Nuclear Medicine Clinic, Basel, Switzerland.
  • Fides Regina Schwartz
    University of Basel, University Hospital Basel, Radiology and Nuclear Medicine Clinic, Basel, Switzerland.
  • Andreas Termer
    University of Heidelberg, Department of General, Visceral and Transplant Surgery, Heidelberg, Germany.
  • Felix Wagner
    University of Heidelberg, Department of General, Visceral and Transplant Surgery, Heidelberg, Germany.
  • Hannes Götz Kenngott
    University of Heidelberg, Department of General, Visceral and Transplant Surgery, Heidelberg, Germany.
  • Lena Maier-Hein
    German Cancer Research Center (DKFZ), Computer Assisted Medical Interventions, Heidelberg, Germany.

Keywords

No keywords available for this article.