The effect of continuous positive airway pressure on pulmonary function may depend on the basal level of forced expiratory volume in 1 second.

Journal: Journal of thoracic disease
Published Date: Dec 1, 2018

Abstract

BACKGROUND: The coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), also referred to as overlap syndrome (OS), is associated with a high rate of morbidity, COPD exacerbations and mortality. Treatment with continuous positive airway pressure (CPAP) has proven to significantly decrease the rate of these complications. However, data concerning the effect of CPAP on pulmonary function are scarce and conflicting. The aim of our study was to evaluate the effect of 1 year of CPAP treatment on arterial blood gases (ABGs) and pulmonary function tests in patients with OS and its potential relationship with the baseline severity of airway obstruction. A secondary aim was to search for predictors of changes in the evaluated parameters.

Authors

  • Annia Schreiber
    Pulmonary Rehabilitation Unit, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
  • Sara Surbone
    Unità Operativa di Pneumologia, Ospedale Asilo Vittoria di Mortara, Azienda Socio Sanitaria Territoriale di Pavia, Italy.
  • Alberto Malovini
    Laboratory of Informatics and Systems Engineering for Clinical Research, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
  • Marco Mancini
    Direzione Sanitaria, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
  • Francesca Cemmi
    Unità Operativa di Pneumologia, Ospedale Pederzoli, Peschiera del Garda (Verona), Italy.
  • Giancarlo Piaggi
    Pulmonary Rehabilitation Unit, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
  • Piero Ceriana
    Pulmonary Rehabilitation Unit, Istituti Clinici Scientifici Maugeri, Pavia, Italy.
  • Annalisa Carlucci
    Pulmonary Rehabilitation Unit, Istituti Clinici Scientifici Maugeri, Pavia, Italy.

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