The TB27 Transcriptomic Model for Predicting Culture Conversion.

Journal: Pathogens & immunity
Published Date:

Abstract

RATIONALE: Treatment monitoring of tuberculosis patients is complicated by a slow growth rate of . Recently, host RNA signatures have been used to monitor the response to tuberculosis treatment.

Authors

  • Maja Reimann
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Korkut Avsar
    Asklepios Fachkliniken München-Gauting, Munich, Germany.
  • Andrew R DiNardo
    The Global Tuberculosis Program, Texas Children's Hospital, Immigrant and Global Health, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
  • Torsten Goldmann
    Division of Histopathology, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.
  • Gunar Günther
    Department of Medicine, University of Namibia School of Medicine, Windhoek, Namibia.
  • Michael Hoelscher
    Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, Munich, Germany.
  • Elmira Ibraim
    Institutul de Pneumoftiziologie "Marius Nasta", MDR-TB Research Department, Bucharest, Romania.
  • Barbara Kalsdorf
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Stefan H E Kaufmann
    Max Planck Institute for Infection Biology, Berlin, Germany.
  • Niklas Köhler
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Anna M Mandalakas
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Florian P Maurer
    National and WHO Supranational Reference Laboratory for Mycobacteria, Research Center Borstel, Borstel, Germany.
  • Marius Müller
    Sankt Katharinen-Krankenhaus, Frankfurt, Germany.
  • Dörte Nitschkowski
    Division of Histopathology, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.
  • Ioana D Olaru
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Cristina Popa
    Institutul de Pneumoftiziologie "Marius Nasta", MDR-TB Research Department, Bucharest, Romania.
  • Andrea Rachow
    Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, Munich, Germany.
  • Thierry Rolling
    Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany.
  • Helmut J F Salzer
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Patricia Sanchez-Carballo
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Maren Schuhmann
    new affiliation: Lungenpraxis Konstanz, Konstanz, Germany.
  • Dagmar Schaub
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Victor Spinu
    Institutul de Pneumoftiziologie "Marius Nasta", MDR-TB Research Department, Bucharest, Romania.
  • Elena Terhalle
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Markus Unnewehr
    Department of Respiratory Medicine and Infectious Diseases, St. Barbara-Klinik, Hamm, Germany.
  • Nika J Zielinski
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Jan Heyckendorf
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.
  • Christoph Lange
    Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.

Keywords

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