Tranexamic acid reduces blood loss after primary shoulder arthroplasty: a double-blind, placebo-controlled, prospective, randomized controlled trial.

Journal: JSES open access
Published Date: Feb 6, 2018

Abstract

BACKGROUND: Tranexamic acid (TXA) is an antifibrinolytic that has been shown to decrease blood loss and transfusion rates after hip and knee arthroplasty, with only limited evidence to support its use in shoulder arthroplasty. This study was conducted to determine whether intravenous (IV) TXA is more effective than placebo in reducing blood loss after primary total shoulder arthroplasty (TSA).

Authors

  • Gregory L Cvetanovich
    Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Yale A Fillingham
    Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Michael O'Brien
    Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Brian Forsythe
    Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Brian J Cole
    Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Nikhil N Verma
    Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Anthony A Romeo
    Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Gregory P Nicholson
    Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.

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