Early Versus Late Conversion From Immediate to Prolonged-Release Tacrolimus After Renal Transplantation: Clinical Effects and Treatment Costs.

Journal: Transplantation direct
Published Date: Dec 20, 2018

Abstract

INTRODUCTION: Prolonged-release tacrolimus (PR-TAC) was associated with improved renal function after transplantation when compared to immediate-release tacrolimus (IR-TAC) although evidence is still scarce. This study aimed to compare clinical outcomes and treatment costs in patients who converted from IR-TAC to PR-TAC during the first year after renal transplantation (RT) (early converters [EC]) or after that period (late converters [LC]).

Authors

  • Luís Mendonça
    Department of Nephrology, São João Hospital Center, EPE, Alameda Prof. Hernâni Monteiro, Porto, Portugal.
  • Hugo Diniz
    Department of Nephrology, São João Hospital Center, EPE, Alameda Prof. Hernâni Monteiro, Porto, Portugal.
  • José Silvano
    Department of Nephrology, São João Hospital Center, EPE, Alameda Prof. Hernâni Monteiro, Porto, Portugal.
  • Sofia Marques
    Department of Nephrology, São João Hospital Center, EPE, Alameda Prof. Hernâni Monteiro, Porto, Portugal.
  • Susana Sampaio
    Department of Nephrology, São João Hospital Center, EPE, Alameda Prof. Hernâni Monteiro, Porto, Portugal.
  • Manuel Pestana
    Department of Nephrology, São João Hospital Center, EPE, Alameda Prof. Hernâni Monteiro, Porto, Portugal.

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