iPromoter-CLA: Identifying promoters and their strength by deep capsule networks with bidirectional long short-term memory.

Journal: Computer methods and programs in biomedicine
Published Date:

Abstract

BACKGROUND AND OBJECTIVE: The promoter is a fragment of DNA and a specific sequence with transcriptional regulation function in DNA. Promoters are located upstream at the transcription start site, which is used to initiate downstream gene expression. So far, promoter identification is mainly achieved by biological methods, which often require more effort. It has become a more effective classification and prediction method to identify promoter types through computational methods.

Authors

  • Zhi-Min Zhang
    College of Mathematics and System Sciences, Xinjiang University, Urumqi, China.
  • Jian-Ping Zhao
    College of Mathematics and System Sciences, Xinjiang University, Urumqi, China. Electronic address: zhaojianping@126.com.
  • Pi-Jing Wei
    Institutes of Physical Science and Information Technology, Anhui University, Hefei, China.
  • Chun-Hou Zheng