iPromoter-CLA: Identifying promoters and their strength by deep capsule networks with bidirectional long short-term memory.
Journal:
Computer methods and programs in biomedicine
Published Date:
Aug 28, 2022
Abstract
BACKGROUND AND OBJECTIVE: The promoter is a fragment of DNA and a specific sequence with transcriptional regulation function in DNA. Promoters are located upstream at the transcription start site, which is used to initiate downstream gene expression. So far, promoter identification is mainly achieved by biological methods, which often require more effort. It has become a more effective classification and prediction method to identify promoter types through computational methods.