Enhanced diagnosing patients suspected of sarcoidosis using a hybrid support vector regression model with bald eagle and chimp optimizers.

Journal: PeerJ. Computer science
Published Date:

Abstract

Searching for a reliable indicator of treatment response in sarcoidosis remains a challenge. The use of the soluble interleukin 2 receptor (sIL-2R) as a measure of disease activity has been proposed by researchers. A machine learning model was aimed to be developed in this study to predict sIL-2R levels based on a patient's serum angiotensin-converting enzyme (ACE) levels, potentially aiding in lung function evaluation. A novel forecasting model (SVR-BE-CO) for sIL-2R prediction is introduced, which combines support vector regression (SVR) with a hybrid optimization model (BES-CO); The hybrid optimization model composed of Bald Eagle Optimizer (BES) and Chimp Optimizer (CO) model. In this forecasting model, the hyper-parameters of the SVR model are optimized by the BES-CO hybrid optimization model, ultimately improving the accuracy of the predicted sIL-2R values. The hybrid forecasting model SVR-BE-CO model was evaluated against various forecasting methods, including Hybrid SVR with Firefly Algorithm (SVR-FFA), decision tree (DT), SVR with Gray Wolf Optimization (SVR-GWO) and random forest (RF). It was demonstrated that the hybrid SVR-BE-CO model surpasses all other methods in terms of accuracy.

Authors

  • Guogang Xie
    Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
  • Hani Attar
    Department of Electrical Engineering, Zarqa University, Zarqa, Jordan.
  • Ayat Alrosan
    School of Computing, Skyline University, Sharjah, United Arab Emirates.
  • Sally Mohammed Farghaly Abdelaliem
    Department of Nursing Management and Education, Princess Nourah bint Abdulrahman, Riyadh, Saudi Arabia.
  • Amany Anwar Saeed Alabdullah
    Department of Maternity and Pediatric Nursing, College of Nursing, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
  • Mohanad Deif
    Department of Artificial Intelligence, College of Information Technology, Misr University for Science & Technology, Cairo, Egypt.

Keywords

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