Antioxidant and xanthine oxidase inhibitory activities of total polyphenols from onion.

Journal: Saudi journal of biological sciences
Published Date: Aug 18, 2017

Abstract

Onions ( L.) comprise a valuable vegetable crop in many countries. Modern scientific research has shown that onions possess many biological activities, including antibacterial, anticancer, hypoglycemic, hypolipidemic, antiplatelet aggregation, and antioxidant activities. The goal of this study was to investigate the impact of total onion polyphenols on antioxidant and xanthine oxidase (XO) inhibitory activities. Total onion polyphenols showed significant antioxidant activity in DPPH, FRAP, and OH-assays (IC [µg/mL]), 43.24, 560.61, and 12.97, respectively). In a X/XO system, antioxidant properties of these polyphenols significantly inhibited XO activity (IC [µg/mL], 17.36). These results indicated that total onion polyphenols showed promising antioxidant and anti-gout properties and might be used as potential, natural drugs against oxidative diseases after successful studies in vivo as well as clinical trials.

Authors

  • Hui Ouyang
    Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China.
  • Kun Hou
    Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, and Key Laboratory of Hunan Forest Products and Chemical Industry Engineering, Jishou University, Jishou 416000, China.
  • Wanxi Peng
    School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, China.
  • Zhenling Liu
    School of Management, Henan University of Technology, Zhengzhou 450001, China.
  • Heping Deng
    School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, China.

Keywords

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