Effects of fermented black ginseng on wound healing mediated by angiogenesis through the mitogen-activated protein kinase pathway in human umbilical vein endothelial cells.

Journal: Journal of ginseng research
Published Date: Jul 25, 2017

Abstract

BACKGROUND: Fermented black ginseng (FBG) is produced through several cycles of steam treatment of raw ginseng, at which point its color turns black. During this process, the original ginsenoside components of raw ginseng (e.g., Re, Rg1, Rb1, Rc, and Rb2) are altered, and less-polar ginsenosides are generated (e.g., Rg3, Rg5, Rk1, and Rh4). The aim of this study was to determine the effect of FBG on wound healing.

Authors

  • Jun Yeon Park
    College of Korean Medicine, Gachon University, Seongnam, Republic of Korea.
  • Dong-Soo Lee
    Institute of Human-Environment Interface Biology, Biomedical Research Institute, Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Chang-Eop Kim
    Department of Physiology, Gachon University College of Korean Medicine, Seongnam, South Korea.
  • Myoung-Sook Shin
    Natural Products Research Institute, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
  • Chang-Seob Seo
    Herbal Medicine Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-gu, Daejeon 34054, Republic of Korea.
  • Hyeun-Kyoo Shin
    K-herb Research Center, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
  • Gwi Seo Hwang
    College of Korean Medicine, Gachon University, Seongnam, Republic of Korea.
  • Jun Min An
    GINSENG BY PHARM Co., Ltd., Wonju, Republic of Korea.
  • Su-Nam Kim
    Natural Products Research Institute, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
  • Ki Sung Kang
    College of Korean Medicine, Gachon University, Seongnam, Republic of Korea.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals