Near-patient coagulation testing to predict bleeding after cardiac surgery: a cohort study.

Journal: Research and practice in thrombosis and haemostasis
Published Date: Jul 25, 2017

Abstract

BACKGROUND: Coagulopathic bleeding is common after cardiac surgery and is associated with increased morbidity, mortality and healthcare costs. Implementation of blood management algorithms in which patients with severe bleeding undergo near-patient coagulation testing results in less overall bleeding and transfusion. However, it is unknown whether there is additional value from pre-emptive near-patient testing to predict whether severe bleeding will occur.

Authors

  • Andrew D Mumford
    School of Cellular and Molecular Medicine University of Bristol Bristol UK.
  • Jessica Harris
    Clinical Trials and Evaluation Unit University of Bristol Bristol UK.
  • Zoe Plummer
    Clinical Trials and Evaluation Unit University of Bristol Bristol UK.
  • Kurtis Lee
    University Hospitals Bristol NHS Foundation Trust, Bristol Bristol UK.
  • Veerle Verheyden
    School of Clinical Sciences University of Bristol Bristol UK.
  • Barnaby C Reeves
    Clinical Trials and Evaluation Unit University of Bristol Bristol UK.
  • Chris A Rogers
    Clinical Trials and Evaluation Unit University of Bristol Bristol UK.
  • Gianni D Angelini
    School of Clinical Sciences University of Bristol Bristol UK.
  • Gavin J Murphy
    Department of Clinical Sciences University of Leicester Leicester UK.

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