Evaluation of Association Between the Serum Levels of MMP-9 and MMP-9/TIMPs With Soluble Forms of Selectins and Itching Induced by Sulfur Mustard.

Journal: Iranian journal of pathology
Published Date: Jan 27, 2017

Abstract

BACKGROUND & OBJECTIVE: Pruritus is the most frequent chronic dermal complication of sulfur mustard (SM), which negatively influences the quality of life. Exact pathophysiology of SM-induced itching is unknown. The current study aimed at evaluating the possible association between SM-induced itching and the serum levels of matrix metalloproteinase (MMP)-9 and their endogenous inhibitors, and serum levels of soluble forms of selectins (sL-, sP-, and sE-selectins) as adhesion molecules involved in the development of different inflammatory reactions.

Authors

  • Nayere Askari
    Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, I.R, Iran.
  • Tooba Ghazanfari
    Immunoregulation Research Center, Shahed University, Tehran, Iran.
  • Mohammad Mehdi Naghizadeh
    Immunoregulation Research Center, Shahed University, Tehran, Iran.
  • Athar Moin
    Immunoregulation Research Center, Shahed University, Tehran, Iran.
  • Ali Khamesipour
    Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran.
  • Shahryar Pourfarzam
    Immunoregulation Research Center, Shahed University, Tehran, Iran.
  • Zuhair Mohammad Hassan
    Dept. of Immunology, Tarbiat Moddares University, Tehran, Iran.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals