Identification of mitophagy-related key genes and their correlation with immune cell infiltration in acute myocardial infarction via bioinformatics analysis.

Journal: Frontiers in cardiovascular medicine
Published Date: Jan 13, 2025

Abstract

BACKGROUND: Acute myocardial infarction (AMI), a subset of acute coronary syndrome, remains the major cause of mortality worldwide. Mitochondrial dysfunction is critically involved in AMI progression, and mitophagy plays a vital role in eliminating damaged mitochondria. This study aimed to explore mitophagy-related biomarkers and their potential molecular basis in AMI.

Authors

  • Zulong Sheng
    Department of Cardiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China.
  • Rui Zhang
    Department of Cardiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China.
  • Zhenjun Ji
    Department of Cardiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China.
  • Zhuyuan Liu
    Department of Cardiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China.
  • Yaqing Zhou
    Department of Cardiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China.

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