Endothelial cell leptin receptors, leptin and interleukin-8 in the pathogenesis of preeclampsia: An in-vitro study.

Journal: Turkish journal of obstetrics and gynecology
Published Date: Dec 30, 2017

Abstract

OBJECTIVE: Increased leptin hormone and leptin receptor may enhance the generation of proinflammatory cytokines by endothelial cells and lead to endothelial dysfunction. This study assessed the umbilical cord endothelial leptin receptor levels in preeclampsia and investigated the effect of leptin on endothelial interleukin-8 (IL-8) production.

Authors

  • Sefa Arlıer
    South Florida University Faculty of Medicine, Department of Obstetrics and Gynecology, Tampa, USA.

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