Effect of Angiotensin-Converting Enzyme Inhibitor/Calcium Antagonist Combination Therapy on Renal Function in Hypertensive Patients With Chronic Kidney Disease: Chikushi Anti-Hypertension Trial - Benidipine and Perindopril.

Journal: Journal of clinical medicine research
Published Date: Dec 30, 2017

Abstract

BACKGROUND: Appropriate blood pressure control suppresses progression of chronic kidney disease (CKD). If an angiotensin-converting enzyme (ACE) inhibitor is ineffective, adding a calcium antagonist is recommended. We compared the long-term effect of two ACE inhibitor/calcium antagonist combinations on renal function in hypertensive patients with CKD.

Authors

  • Tetsu Okuda
    Department of Cardiovascular Disease, Fukuoka University Chikushi Hospital, 1-1-1, Zokumyoin, Chikusino-shi, Fukuoka 818-8502, Japan.
  • Keisuke Okamura
    Department of Cardiovascular Disease, Fukuoka University Chikushi Hospital, 1-1-1, Zokumyoin, Chikusino-shi, Fukuoka 818-8502, Japan.
  • Kazuyuki Shirai
    Department of Cardiovascular Disease, Fukuoka University Chikushi Hospital, 1-1-1, Zokumyoin, Chikusino-shi, Fukuoka 818-8502, Japan.
  • Hidenori Urata
    Department of Cardiovascular Disease, Fukuoka University Chikushi Hospital, 1-1-1, Zokumyoin, Chikusino-shi, Fukuoka 818-8502, Japan.

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